| HGNC approved symbol | KAT5 |
| HGNC ID | HGNC:5275 |
| HGNC approved name | K(lysine) acetyltransferase 5 |
| Entrez gene ID | GeneID:10524 (SSTAR profile) |
| UniProt AC (human) | Q92993 |
| UniProt ID (human) | KAT5_HUMAN |
| Pfam domains | Tudor-knot PF11717 (7-65) zf-MYST PF17772 (229-283) MOZ_SAS PF01853 (288-470) |
| MGI symbol | Kat5 |
| MGI ID | MGI:1932051 |
| UniProt AC (mouse) | Q8CHK4 |
| UniProt ID (mouse) | KAT5_MOUSE |
| HGNC gene family tag | KAT, ZC2HC |
| HGNC gene family description | Chromatin-modifying enzymes / K-acetyltransferases, Zinc fingers, C2HC-type containing |
| Function | Histone modification write |
| Modification | Histone acetylation |
| PMID for information on function | PMID:10096020 |
| Protein complex | SWR, NuA4, Piccolo_NuA4 |
| Target molecule | histone |
| Target entity | H2AK5, H3K14, H4K5,H4K8, H4K12, H4K16 |
| Product | H2AK5ac, H3K14ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac |
| PMID for information on target | PMID:10096020 |
| Comment | Tip60=KAT5 significantly acetylates amino-terminal tail peptides of histones H2A, H3 and H4, but not H2B, consistent with substrate preference on intact histones. Preferred acetylation sites for Tip60 are the Lys-5 of histone H2A, the Lys-14 of histone H3, and the Lys-5, -8, -12, -16 of histone H4. |
| Status of entry | # |
| Expression range: | 0.0 to 35.07 |
| Mean expression: | 9.05 ± 4.26 |
| Median expression: | 8.41 |