HGNC approved symbol | KDM1B |
HGNC ID | HGNC:21577 |
HGNC approved name | lysine (K)-specific demethylase 1B |
Entrez gene ID | GeneID:221656 (SSTAR profile) |
UniProt AC (human) | Q8NB78 |
UniProt ID (human) | KDM1B_HUMAN |
Pfam domains | zf-CW PF07496 (137-189) SWIRM PF04433 (292-364) Amino_oxidase PF01593 (392-819) |
MGI symbol | Kdm1b |
MGI ID | MGI:2145261 |
UniProt AC (mouse) | Q8CIG3 |
UniProt ID (mouse) | KDM1B_MOUSE |
HGNC gene family tag | KDM |
HGNC gene family description | Chromatin-modifying enzymes / K-demethylases |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:19727073 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K4me1, H3K4me2 |
Product | H3K4 |
PMID for information on target | PMID:19727073 |
Comment | KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. |
Status of entry | # |
Expression range: | 0.0 to 148.91 |
Mean expression: | 12.53 ± 13.26 |
Median expression: | 8.98 |