HGNC approved symbol | KDM2B |
HGNC ID | HGNC:13610 |
HGNC approved name | lysine (K)-specific demethylase 2B |
Entrez gene ID | GeneID:84678 (SSTAR profile) |
UniProt AC (human) | Q8NHM5 |
UniProt ID (human) | KDM2B_HUMAN |
Pfam domains | Cupin_8 PF13621 (150-331) JHD PF17811 (334-375) zf-CXXC PF02008 (607-651) PHD_4 PF16866 (657-723) F-box-like PF12937 (1068-1107) |
MGI symbol | Kdm2b |
MGI ID | MGI:1354737 |
UniProt AC (mouse) | Q6P1G2 |
UniProt ID (mouse) | KDM2B_MOUSE |
HGNC gene family tag | FBXL, KDM |
HGNC gene family description | F-boxes / Leucine-rich repeats, Chromatin-modifying enzymes / K-demethylases |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:17994099 |
Protein complex | BCOR |
Target molecule | histone |
Target entity | H3K4me3, H3K36me2 |
Product | H3K4, H3K36 |
PMID for information on target | PMID:17994099 |
Comment | JHDM1B =KDM2B is a histone demethylase that catalyses the demethylation of H3K4me3. |
Status of entry | # |
Expression range: | 0.67 to 233.41 |
Mean expression: | 13.95 ± 14.55 |
Median expression: | 10.51 |