HGNC approved symbol | KDM3B |
HGNC ID | HGNC:1337 |
HGNC approved name | lysine (K)-specific demethylase 3B |
Entrez gene ID | GeneID:51780 (SSTAR profile) |
UniProt AC (human) | Q7LBC6 |
UniProt ID (human) | KDM3B_HUMAN |
Pfam domains | domain PF22989 (10-83) domain PF22988 (91-188) domain PF22987 (189-254) JmjC PF02373 (1599-1704) |
MGI symbol | Kdm3b |
MGI ID | MGI:1923356 |
UniProt AC (mouse) | Q6ZPY7 |
UniProt ID (mouse) | KDM3B_MOUSE |
HGNC gene family tag | KDM |
HGNC gene family description | Chromatin-modifying enzymes / K-demethylases |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:16603237 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9me1, H3K9me2 |
Product | H3K9 |
PMID for information on target | PMID:16603237 |
Comment | A JmjC domain-containing protein (KDM3B=JmjC domain-containing histone demethylation protein 2B), JHDM2A, which specifically demethylates mono- and dimethyl-H3K9. |
Status of entry | # |
Expression range: | 0.0 to 68.81 |
Mean expression: | 10.28 ± 5.69 |
Median expression: | 9.12 |