HGNC approved symbol | KDM4C |
HGNC ID | HGNC:17071 |
HGNC approved name | lysine (K)-specific demethylase 4C |
Entrez gene ID | GeneID:23081 (SSTAR profile) |
UniProt AC (human) | Q9H3R0 |
UniProt ID (human) | KDM4C_HUMAN |
Pfam domains | JmjN PF02375 (17-51) JmjC PF02373 (177-293) PHD_2 PF13831 (712-747) zf-HC5HC2H_2 PF13832 (754-864) Tudor_2 PF18104 (881-916, 939-974) |
MGI symbol | Kdm4c |
MGI ID | MGI:1924054 |
UniProt AC (mouse) | Q8VCD7 |
UniProt ID (mouse) | KDM4C_MOUSE |
HGNC gene family tag | KDM, TDRD |
HGNC gene family description | Chromatin-modifying enzymes / K-demethylases, Tudor domain containing |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:16603238 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9me3, H3K36me3 |
Product | H3K9me1, H3K9me2 |
PMID for information on target | PMID:16603238 |
Comment | Human JMJD2(B, C, D) =KDM4(B, C, D) subfamily members function as trimethylation-specific demethylases, converting H3-K9Me3 to H3-K9Me2 and H3-K9Me1, respectively. |
Status of entry | # |
Expression range: | 0.0 to 196.95 |
Mean expression: | 26.87 ± 24.57 |
Median expression: | 17.26 |