HGNC approved symbol | KDM4D |
HGNC ID | HGNC:25498 |
HGNC approved name | lysine (K)-specific demethylase 4D |
Entrez gene ID | GeneID:55693 (SSTAR profile) |
UniProt AC (human) | Q6B0I6 |
UniProt ID (human) | KDM4D_HUMAN |
Pfam domains | JmjN PF02375 (19-53) JmjC PF02373 (179-295) |
MGI symbol | Kdm4d |
MGI ID | MGI:3606484 |
UniProt AC (mouse) | Q3U2K5 |
UniProt ID (mouse) | KDM4D_MOUSE |
HGNC gene family tag | KDM |
HGNC gene family description | Chromatin-modifying enzymes / K-demethylases |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:16603238 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9me3 |
Product | H3K9me1, H3K9me2 |
PMID for information on target | PMID:16603238 |
Comment | Human JMJD2(B, C, D) =KDM4(B, C, D) subfamily members function as trimethylation-specific demethylases, converting H3-K9Me3 to H3-K9Me2 and H3-K9Me1, respectively. |
Status of entry | # |
Expression range: | 0.0 to 43.68 |
Mean expression: | 0.84 ± 2.06 |
Median expression: | 0.6 |