HGNC approved symbol | KDM4E |
HGNC ID | HGNC:37098 |
HGNC approved name | lysine (K)-specific demethylase 4E |
Entrez gene ID | GeneID:390245 (SSTAR profile) |
UniProt AC (human) | B2RXH2 |
UniProt ID (human) | KDM4E_HUMAN |
Pfam domains | JmjN PF02375 (16-50) JmjC PF02373 (176-292) |
MGI symbol | # |
MGI ID | MGI:# |
UniProt AC (mouse) | # |
UniProt ID (mouse) | # |
HGNC gene family tag | KDM |
HGNC gene family description | Chromatin-modifying enzymes / K-demethylases |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:21914792 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9me2, H3K9me3 |
Product | H3K9 |
PMID for information on target | PMID:21914792 |
Comment | KDM4D and KDM4E (which is catalytically active) catalyze demethylation of H3K9me3/me2. |
Status of entry | # |