| HGNC approved symbol | KDM5C |
| HGNC ID | HGNC:11114 |
| HGNC approved name | lysine (K)-specific demethylase 5C |
| Entrez gene ID | GeneID:8242 (SSTAR profile) |
| UniProt AC (human) | P41229 |
| UniProt ID (human) | KDM5C_HUMAN |
| Pfam domains | JmjN PF02375 (15-48) ARID PF01388 (80-165) PHD PF00628 (327-371) JmjC PF02373 (501-617) KDM5_C-hel PF21323 (621-675) zf-C5HC2 PF02928 (707-759) PLU-1 PF08429 (771-1098) |
| MGI symbol | Kdm5c |
| MGI ID | MGI:99781 |
| UniProt AC (mouse) | P41230 |
| UniProt ID (mouse) | KDM5C_MOUSE |
| HGNC gene family tag | KDM, PHF |
| HGNC gene family description | Chromatin-modifying enzymes / K-demethylases, Zinc fingers, PHD-type |
| Function | Histone modification erase |
| Modification | Histone methylation |
| PMID for information on function | PMID:17320160 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K4me3 |
| Product | H3K4me2, H3K4me1 |
| PMID for information on target | PMID:17320160 |
| Comment | The X-linked mental retardation (XLMR) gene SMCX (JARID1C)=KDM5C, which encodes a JmjC-domain protein, reverses H3K4me3 to di- and mono- but not unmethylated products. |
| Status of entry | # |
| Expression range: | 3.65 to 104.51 |
| Mean expression: | 35.37 ± 14.77 |
| Median expression: | 32.71 |