HGNC approved symbol | KDM5D |
HGNC ID | HGNC:11115 |
HGNC approved name | lysine (K)-specific demethylase 5D |
Entrez gene ID | GeneID:8284 (SSTAR profile) |
UniProt AC (human) | Q9BY66 |
UniProt ID (human) | KDM5D_HUMAN |
Pfam domains | JmjN PF02375 (15-48) ARID PF01388 (81-165) PHD PF00628 (317-361) JmjC PF02373 (491-607) KDM5_C-hel PF21323 (611-665) zf-C5HC2 PF02928 (697-749) PLU-1 PF08429 (763-1085) |
MGI symbol | Kdm5d |
MGI ID | MGI:99780 |
UniProt AC (mouse) | Q62240 |
UniProt ID (mouse) | KDM5D_MOUSE |
HGNC gene family tag | KDM, PHF |
HGNC gene family description | Chromatin-modifying enzymes / K-demethylases, Zinc fingers, PHD-type |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:17320160 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K4me3, H3K4me2 |
Product | H3K4 |
PMID for information on target | PMID:17320160 |
Comment | SMCX family members, including SMCY=KDM5D, RBP2, and PLU-1, demethylate H3K4me3. |
Status of entry | # |
Expression range: | 0.0 to 87.27 |
Mean expression: | 8.43 ± 13.16 |
Median expression: | 0.0 |