HGNC approved symbol | KDM8 |
HGNC ID | HGNC:25840 |
HGNC approved name | lysine (K)-specific demethylase 8 |
Entrez gene ID | GeneID:79831 (SSTAR profile) |
UniProt AC (human) | Q8N371 |
UniProt ID (human) | KDM8_HUMAN |
Pfam domains | Cupin_8 PF13621 (194-416) |
MGI symbol | Kdm8 |
MGI ID | MGI:1924285 |
UniProt AC (mouse) | Q9CXT6 |
UniProt ID (mouse) | KDM8_MOUSE |
HGNC gene family tag | KDM |
HGNC gene family description | Chromatin-modifying enzymes / K-demethylases |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:20457893 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K36me2 |
Product | H3K36 |
PMID for information on target | PMID:20457893 |
Comment | JMJD5 (now renamed KDM8), a JmjC family member, demethylates H3K36me2 and is required for cell cycle progression. |
Status of entry | # |