| HGNC approved symbol | KMT2A |
| HGNC ID | HGNC:7132 |
| HGNC approved name | lysine (K)-specific methyltransferase 2A |
| Entrez gene ID | GeneID:4297 (SSTAR profile) |
| UniProt AC (human) | Q03164 |
| UniProt ID (human) | KMT2A_HUMAN |
| Pfam domains | zf-CXXC PF02008 (1149-1194) PHD PF00628 (1481-1530, 1569-1624) zf-HC5HC2H PF13771 (1897-1978) FYRN PF05964 (2016-2077) FYRC PF05965 (3666-3747) SET PF00856 (3840-3945) |
| MGI symbol | Kmt2a |
| MGI ID | MGI:96995 |
| UniProt AC (mouse) | P55200 |
| UniProt ID (mouse) | KMT2A_MOUSE |
| HGNC gene family tag | KMT, PHF |
| HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases, Zinc fingers, PHD-type |
| Function | Histone modification write |
| Modification | Histone methylation |
| PMID for information on function | PMID:19187761 |
| Protein complex | MLL-HCF, CHD8, COMPASS-like MLL1,2 |
| Target molecule | histone |
| Target entity | H3K4 |
| Product | H3K4me |
| PMID for information on target | PMID:19187761 |
| Comment | MLL1 SET domain can incorporate methyl groups into unmodified or H3K4me1 substrates, signifying both mono- and dimethylation activity. |
| Status of entry | # |
| Expression range: | 2.11 to 186.66 |
| Mean expression: | 34.48 ± 23.26 |
| Median expression: | 27.11 |