HGNC approved symbol | KMT2B |
HGNC ID | HGNC:15840 |
HGNC approved name | lysine (K)-specific methyltransferase 2B |
Entrez gene ID | GeneID:9757 (SSTAR profile) |
UniProt AC (human) | Q9UMN6 |
UniProt ID (human) | KMT2B_HUMAN |
Pfam domains | zf-CXXC PF02008 (959-1005) PHD PF00628 (1203-1250, 1251-1300, 1337-1393) zf-HC5HC2H PF13771 (1605-1685) FYRN PF05964 (1731-1784) FYRC PF05965 (2415-2494) SET PF00856 (2580-2691) |
MGI symbol | Kmt2b |
MGI ID | MGI:109565 |
UniProt AC (mouse) | O08550 |
UniProt ID (mouse) | KMT2B_MOUSE |
HGNC gene family tag | KMT |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:17707229 |
Protein complex | Menin-associated_HMT, MLL2/3, COMPASS-like MLL3,4 |
Target molecule | histone |
Target entity | H3K4 |
Product | H3K4me3 |
PMID for information on target | PMID:17707229 |
Comment | MLL (=KMT2B)-containing complexes methylate histone H3 at lysine 4 (H3K4) and have been implicated in the regulation of transcription. |
Status of entry | # |
Expression range: | N/A |
Mean expression: | N/A |
Median expression: | N/A |
Sample class | Sample | Expression (RLE-normalized CAGE tags per million) | Quantile over all genes |
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