Gene info
HGNC approved symbolKMT2B
HGNC IDHGNC:15840
HGNC approved namelysine (K)-specific methyltransferase 2B
Entrez gene IDGeneID:9757
(SSTAR profile)
UniProt AC (human)Q9UMN6
UniProt ID (human)KMT2B_HUMAN
Pfam domainszf-CXXC PF02008 (959-1005)
PHD PF00628 (1203-1250, 1251-1300, 1337-1393)
zf-HC5HC2H PF13771 (1605-1685)
FYRN PF05964 (1731-1784)
FYRC PF05965 (2415-2494)
SET PF00856 (2580-2691)
MGI symbolKmt2b
MGI IDMGI:109565
UniProt AC (mouse)O08550
UniProt ID (mouse)KMT2B_MOUSE
HGNC gene family tagKMT
HGNC gene family descriptionChromatin-modifying enzymes / K-methyltransferases
FunctionHistone modification write
ModificationHistone methylation
PMID for information on functionPMID:17707229
Protein complexMenin-associated_HMT, MLL2/3, COMPASS-like MLL3,4
Target moleculehistone
Target entityH3K4
ProductH3K4me3
PMID for information on targetPMID:17707229
CommentMLL (=KMT2B)-containing complexes methylate histone H3 at lysine 4 (H3K4) and have been implicated in the regulation of transcription.
Status of entry#

Expression statistics
Expression range: N/A
Mean expression: N/A
Median expression: N/A
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes