| HGNC approved symbol | KMT2E |
| HGNC ID | HGNC:18541 |
| HGNC approved name | lysine (K)-specific methyltransferase 2E |
| Entrez gene ID | GeneID:55904 (SSTAR profile) |
| UniProt AC (human) | Q8IZD2 |
| UniProt ID (human) | KMT2E_HUMAN |
| Pfam domains | PHD_5 PF20826 (118-164) SET PF00856 (343-447) |
| MGI symbol | Kmt2e |
| MGI ID | MGI:1924825 |
| UniProt AC (mouse) | Q3UG20 |
| UniProt ID (mouse) | KMT2E_MOUSE |
| HGNC gene family tag | KMT, PHF |
| HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases, Zinc fingers, PHD-type |
| Function | Histone modification write |
| Modification | Histone methylation |
| PMID for information on function | PMID:19377461 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K4 |
| Product | H3K4me1, H3K4me2 |
| PMID for information on target | PMID:19377461 |
| Comment | Nuclear GlcNAcylation of the histone lysine methyltransferase (HKMT), MLL5, by O-GlcNAc transferase facilitates retinoic-acid-induced granulopoiesis in human HL60 promyelocytes through methylation of H3K4. |
| Status of entry | # |
| Expression range: | 2.53 to 376.15 |
| Mean expression: | 38.52 ± 36.21 |
| Median expression: | 25.9 |