| HGNC approved symbol | LRWD1 |
| HGNC ID | HGNC:21769 |
| HGNC approved name | leucine-rich repeats and WD repeat domain containing 1 |
| Entrez gene ID | GeneID:222229 (SSTAR profile) |
| UniProt AC (human) | Q9UFC0 |
| UniProt ID (human) | LRWD1_HUMAN |
| Pfam domains | domain PF12799 (48-104) WD40 PF00400 (384-421) |
| MGI symbol | Lrwd1 |
| MGI ID | MGI:1918985 |
| UniProt AC (mouse) | Q8BUI3 |
| UniProt ID (mouse) | LRWD1_MOUSE |
| HGNC gene family tag | WDR |
| HGNC gene family description | WD repeat domain containing |
| Function | Chromatin remodeling |
| Modification | # |
| PMID for information on function | PMID:20932478 |
| Protein complex | # |
| Target molecule | histone, DNA |
| Target entity | H3K9me3, H3K27me3 |
| Product | # |
| PMID for information on target | PMID:20932478 |
| Comment | A highly conserved, leucine-rich repeats and WD40 repeat domain-containing protein 1 (LRWD1) or ORC-associated (ORCA) in human cells that interacts with ORC and modulates chromatin association of ORC. ORCA colocalizes with ORC and shows similar cell-cycle dynamics. ORCA efficiently recruits ORC to chromatin. |
| Status of entry | # |
| Expression range: | 1.35 to 468.67 |
| Mean expression: | 15.46 ± 21.85 |
| Median expression: | 12.78 |