| HGNC approved symbol | MBNL1 |
| HGNC ID | HGNC:6923 |
| HGNC approved name | Muscleblind-like protein 1 (Triplet-expansion RNA-binding protein) |
| Entrez gene ID | GeneID:4154 (SSTAR profile) |
| UniProt AC (human) | Q9NR56 |
| UniProt ID (human) | MBNL1_HUMAN |
| Pfam domains | zf-CCCH_2 PF14608 (19-39) domain PF22628 (48-86, 216-253) zf-CCCH PF00642 (183-205) |
| MGI symbol | Mbnl1 |
| MGI ID | MGI:1928482 |
| UniProt AC (mouse) | Q9JKP5 |
| UniProt ID (mouse) | MBNL1_MOUSE |
| HGNC gene family tag | ZC3H |
| HGNC gene family description | Zinc fingers CCCH-type |
| Function | RNA modification |
| Modification | Alternative splicing |
| PMID for information on function | PMID:16946708, PMID:19470458, PMID:15257297 |
| Protein complex | # |
| Target molecule | RNA |
| Target entity | mRNA |
| Product | # |
| PMID for information on target | PMID:16946708, PMID:19470458, PMID:15257297 |
| Comment | Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonistic regulator with CELF proteins. |
| Status of entry | New |
| Expression range: | 0.0 to 1788.01 |
| Mean expression: | 202.35 ± 188.38 |
| Median expression: | 145.48 |