Gene info
| HGNC approved symbol | MECP2 |
| HGNC ID | HGNC:6990 |
| HGNC approved name | methyl CpG binding protein 2 |
| Entrez gene ID | GeneID:4204 (SSTAR profile) |
| UniProt AC (human) | P51608 |
| UniProt ID (human) | MECP2_HUMAN |
| Pfam domains | MBD PF01429 (97-159) |
| MGI symbol | Mecp2 |
| MGI ID | MGI:99918 |
| UniProt AC (mouse) | Q9Z2D6 |
| UniProt ID (mouse) | MECP2_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification write cofactor, Histone modification write cofactor, TF |
| Modification | Histone methylation, Histone acetylation, TF repressor |
| PMID for information on function | PMID:10773092 |
| Protein complex | # |
| Target molecule | DNA |
| Target entity | mCG, DNA motif |
| HOCOMOCO TFBS model | |
| Product | # |
| PMID for information on target | PMID:10773092 |
| Comment | Methyl-CpG-binding protein 2 (MeCP2) contains a transcriptional repression domain (TRD), which can act by recruitment of a large transcriptional co-repressor complex containing histone deacetylases HDAC1 and 2. |
| Status of entry | # |
Expression statistics
| Expression range: | 7.97 to 258.9 |
| Mean expression: | 34.16 ± 29.26 |
| Median expression: | 24.94 |