HGNC approved symbol | MEN1 |
HGNC ID | HGNC:7010 |
HGNC approved name | multiple endocrine neoplasia I |
Entrez gene ID | GeneID:# (SSTAR profile) |
UniProt AC (human) | O00255 |
UniProt ID (human) | MEN1_HUMAN |
Pfam domains | Menin PF05053 (4-499, 550-610) |
MGI symbol | Men1 |
MGI ID | MGI:1316736 |
UniProt AC (mouse) | O88559 |
UniProt ID (mouse) | MEN1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write cofactor |
Modification | Histone methylation |
PMID for information on function | PMID:14992727 |
Protein complex | Menin-associated_HMT, MLL-HCF, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7 |
Target molecule | histone |
Target entity | H3K4 |
Product | H3K4me |
PMID for information on target | PMID:14992727, PMID:15199122 |
Comment | Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4) (UniProt). |
Status of entry | # |