| HGNC approved symbol | MPHOSPH8 |
| HGNC ID | HGNC:29810 |
| HGNC approved name | M-phase phosphoprotein 8 |
| Entrez gene ID | GeneID:54737 (SSTAR profile) |
| UniProt AC (human) | Q99549 |
| UniProt ID (human) | MPP8_HUMAN |
| Pfam domains | Chromo PF00385 (59-108) Ank_2 PF12796 (571-665) Ank PF00023 (666-695) |
| MGI symbol | Mphosph8 |
| MGI ID | MGI:1922589 |
| UniProt AC (mouse) | Q3TYA6 |
| UniProt ID (mouse) | MPP8_MOUSE |
| HGNC gene family tag | ANKRD |
| HGNC gene family description | Ankyrin repeat domain containing |
| Function | Histone modification read |
| Modification | # |
| PMID for information on function | PMID:21419134 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K9me3, H3K9me2 |
| Product | # |
| PMID for information on target | PMID:21419134 |
| Comment | M-phase phosphoprotein 8 (MPP8=MPHOSPH8) harbors an N-terminal chromodomain and a C-terminal ankyrin repeat domain. MPP8, via its chromodomain, binds histone H3 peptide tri- or di-methylated at lysine 9 (H3K9me3/H3K9me2) in submicromolar affinity. |
| Status of entry | # |
| Expression range: | 0.0 to 231.55 |
| Mean expression: | 20.48 ± 19.4 |
| Median expression: | 14.31 |