HGNC approved symbol | MTA2 |
HGNC ID | HGNC:7411 |
HGNC approved name | metastasis associated 1 family, member 2 |
Entrez gene ID | GeneID:9219 (SSTAR profile) |
UniProt AC (human) | O94776 |
UniProt ID (human) | MTA2_HUMAN |
Pfam domains | BAH PF01426 (4-142) ELM2 PF01448 (147-199) Myb_DNA-binding PF00249 (266-311) GATA PF00320 (367-403) MTA_R1 PF17226 (450-525) |
MGI symbol | Mta2 |
MGI ID | MGI:1346340 |
UniProt AC (mouse) | Q9R190 |
UniProt ID (mouse) | MTA2_MOUSE |
HGNC gene family tag | GATAD |
HGNC gene family description | GATA zinc finger domain containing |
Function | Histone modification erase cofactor |
Modification | Histone acetylation |
PMID for information on function | PMID:10444591 |
Protein complex | NuRD |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:10444591 |
Comment | MTA2 directs the assembly of an active histone deacetylase complex, and the association of MTA2 with the core HDAC/RbAp complex requires MBD3. |
Status of entry | # |
Expression range: | 9.75 to 212.13 |
Mean expression: | 59.35 ± 27.2 |
Median expression: | 53.1 |