HGNC approved symbol | NBN |
HGNC ID | HGNC:7652 |
HGNC approved name | nibrin |
Entrez gene ID | GeneID:4683 (SSTAR profile) |
UniProt AC (human) | O60934 |
UniProt ID (human) | NBN_HUMAN |
Pfam domains | FHA PF00498 (24-100) BRCT PF00533 (114-181) NIBRIN_BRCT_II PF16508 (217-323) Nbs1_C PF08599 (685-749) |
MGI symbol | Nbn |
MGI ID | MGI:1351625 |
UniProt AC (mouse) | Q9R207 |
UniProt ID (mouse) | NBN_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:19338747 |
Protein complex | # |
Target molecule | histone |
Target entity | H2AX |
Product | # |
PMID for information on target | # |
Comment | Interacts with H2AX. UniProt: It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. |
Status of entry | # |
Expression range: | 1.54 to 1240.9 |
Mean expression: | 42.24 ± 62.22 |
Median expression: | 34.06 |