HGNC approved symbol | NPM1 |
HGNC ID | HGNC:7910 |
HGNC approved name | nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
Entrez gene ID | GeneID:4869 (SSTAR profile) |
UniProt AC (human) | P06748 |
UniProt ID (human) | NPM_HUMAN |
Pfam domains | Nucleoplasmin PF03066 (17-117) NPM1-C PF16276 (244-293) |
MGI symbol | Npm1 |
MGI ID | MGI:106184 |
UniProt AC (mouse) | Q61937 |
UniProt ID (mouse) | NPM_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone chaperone |
Modification | # |
PMID for information on function | PMID:25349213 |
Protein complex | # |
Target molecule | histone |
Target entity | H3, H2B, H4 |
Product | # |
PMID for information on target | # |
Comment | Co-immunoprecipitation shows that NPM1 is associated with HP1γ, core and linker histones. Uniprot: Acts as a chaperonin for the core histones H3, H2B and H4. |
Status of entry | # |
Expression range: | 2.99 to 1224.74 |
Mean expression: | 294.16 ± 197.54 |
Median expression: | 247.48 |