| HGNC approved symbol | NSD1 |
| HGNC ID | HGNC:14234 |
| HGNC approved name | nuclear receptor binding SET domain protein 1 |
| Entrez gene ID | GeneID:64324 (SSTAR profile) |
| UniProt AC (human) | Q96L73 |
| UniProt ID (human) | NSD1_HUMAN |
| Pfam domains | PWWP PF00855 (318-408, 1756-1846) domain PF23011 (1542-1587) domain PF22908 (1591-1639) domain PF23004 (1640-1692) PHD PF00628 (1710-1748) AWS PF17907 (1900-1940) SET PF00856 (1953-2059) C5HCH PF17982 (2162-2210) |
| MGI symbol | Nsd1 |
| MGI ID | MGI:1276545 |
| UniProt AC (mouse) | O88491 |
| UniProt ID (mouse) | NSD1_MOUSE |
| HGNC gene family tag | KMT, PHF |
| HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases, Zinc fingers, PHD-type |
| Function | Histone modification write |
| Modification | Histone methylation |
| PMID for information on function | PMID:21196496 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K36, H4K20 |
| Product | H3K36me, H4K20me |
| PMID for information on target | PMID:21196496 |
| Comment | NSD1 is a SET domain histone methyltransferase that primarily dimethylates nucleosomal histone H3 lysine 36 (H3K36). |
| Status of entry | # |
| Expression range: | 0.0 to 134.13 |
| Mean expression: | 17.38 ± 9.49 |
| Median expression: | 16.17 |