HGNC approved symbol | NSL1 |
HGNC ID | HGNC:24548 |
HGNC approved name | NSL1, MIS12 kinetochore complex component |
Entrez gene ID | GeneID:25936 (SSTAR profile) |
UniProt AC (human) | Q96IY1 |
UniProt ID (human) | NSL1_HUMAN |
Pfam domains | Mis14 PF08641 (80-190) |
MGI symbol | Nsl1 |
MGI ID | MGI:2685830 |
UniProt AC (mouse) | Q8K305 |
UniProt ID (mouse) | NSL1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write cofactor |
Modification | Histone acetylation |
PMID for information on function | PMID:20018852 |
Protein complex | # |
Target molecule | histone |
Target entity | H4K16 |
Product | H4K16ac |
PMID for information on target | PMID:20018852 |
Comment | Binding of NSL1 to MOF enhances MOF acetylation of histone H4 on lysine 16 and of the DNA binding transcription factor p53. |
Status of entry | # |