| HGNC approved symbol | PADI4 |
| HGNC ID | HGNC:18368 |
| HGNC approved name | peptidyl arginine deiminase, type IV |
| Entrez gene ID | GeneID:23569 (SSTAR profile) |
| UniProt AC (human) | Q9UM07 |
| UniProt ID (human) | PADI4_HUMAN |
| Pfam domains | PAD_N PF08526 (1-113) PAD_M PF08527 (113-275) PAD PF03068 (286-661) |
| MGI symbol | Padi4 |
| MGI ID | MGI:1338898 |
| UniProt AC (mouse) | Q9Z183 |
| UniProt ID (mouse) | PADI4_MOUSE |
| HGNC gene family tag | PADI |
| HGNC gene family description | Peptidyl arginine deiminases |
| Function | Histone modification |
| Modification | Histone citrullination |
| PMID for information on function | PMID:15339660 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H2AR, H3R2, H3R8, H3R17, H3R26, H4R |
| Product | H2ARci, H3R2ci, H3R8ci, H3R17ci, H3R26ci, H4Rci |
| PMID for information on target | PMID:15339660 |
| Comment | Deimination converts histone arginine to citrulline and antagonizes arginine methylation. Peptidyl arginine deiminase 4 (PADI4) specifically deiminates, arginine residues R2, R8, R17, and R26 in the H3 tail. Deimination by PADI4 prevents arginine methylation by CARM1. |
| Status of entry | # |
| Expression range: | 0.0 to 299.16 |
| Mean expression: | 3.86 ± 19.94 |
| Median expression: | 0.0 |