HGNC approved symbol | PAF1 |
HGNC ID | HGNC:25459 |
HGNC approved name | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
Entrez gene ID | GeneID:54623 (SSTAR profile) |
UniProt AC (human) | Q8N7H5 |
UniProt ID (human) | PAF1_HUMAN |
Pfam domains | Paf1 PF03985 (31-420) |
MGI symbol | Paf1 |
MGI ID | MGI:1923988 |
UniProt AC (mouse) | Q8K2T8 |
UniProt ID (mouse) | PAF1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write cofactor |
Modification | Histone ubiquitination |
PMID for information on function | PMID:16307923 |
Protein complex | # |
Target molecule | histone |
Target entity | H2, H3 |
Product | # |
PMID for information on target | # |
Comment | Involved in H2 and H3 ubiquitination. Involved in H2 and H3 ubiquitination. UniProt: PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). |
Status of entry | # |