HGNC approved symbol | PARG |
HGNC ID | HGNC:8605 |
HGNC approved name | poly (ADP-ribose) glycohydrolase |
Entrez gene ID | GeneID:8505 (SSTAR profile) |
UniProt AC (human) | Q86W56 |
UniProt ID (human) | PARG_HUMAN |
Pfam domains | PARG_cat_N PF20811 (582-699) PARG_cat_C PF05028 (705-909) |
MGI symbol | Parg |
MGI ID | MGI:1347094 |
UniProt AC (mouse) | O88622 |
UniProt ID (mouse) | PARG_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:23102699, PMID:21398629 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9 |
Product | # |
PMID for information on target | PMID:23102699, PMID:21398629 |
Comment | Reverses PARP activity. Both PAR and PARP-1 have an influence on PARG recruitment. Also recruitment through a PBD-mediated interaction of PARG with PCNA. |
Status of entry | # |