| HGNC approved symbol | PAXIP1 |
| HGNC ID | HGNC:8624 |
| HGNC approved name | PAX interacting (with transcription-activation domain) protein 1 |
| Entrez gene ID | GeneID:22976 (SSTAR profile) |
| UniProt AC (human) | Q6ZW49 |
| UniProt ID (human) | PAXI1_HUMAN |
| Pfam domains | PTCB-BRCT PF12738 (102-165, 710-771) BRCT PF00533 (604-684) RTT107_BRCT_5 PF16770 (860-947) BRCT_2 PF16589 (973-1062) |
| MGI symbol | Paxip1 |
| MGI ID | MGI:1890430 |
| UniProt AC (mouse) | Q6NZQ4 |
| UniProt ID (mouse) | PAXI1_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification write cofactor |
| Modification | Histone methylation |
| PMID for information on function | PMID:17178841 |
| Protein complex | CHD8, MLL2/3, MLL4/WBP7, COMPASS-like MLL3,4 |
| Target molecule | histone |
| Target entity | H3K4 |
| Product | H3K4me3 |
| PMID for information on target | PMID:17178841 |
| Comment | ALR (MLL2) is a member of the human MLL family, which belongs to a larger SET1 family of histone methyltransferases. ALR is present within a stable multiprotein complex containing a cohort of proteins shared with other SET1 family complexes and several unique components, such as PTIP and the jumonji family member UTX. |
| Status of entry | # |
| Expression range: | 0.0 to 24.41 |
| Mean expression: | 4.15 ± 2.99 |
| Median expression: | 3.43 |