HGNC approved symbol | PBK |
HGNC ID | HGNC:18282 |
HGNC approved name | PDZ binding kinase |
Entrez gene ID | GeneID:55872 (SSTAR profile) |
UniProt AC (human) | Q96KB5 |
UniProt ID (human) | TOPK_HUMAN |
Pfam domains | Pkinase PF00069 (35-317) |
MGI symbol | Pbk |
MGI ID | MGI:1289156 |
UniProt AC (mouse) | Q9JJ78 |
UniProt ID (mouse) | TOPK_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:16982762 |
Protein complex | # |
Target molecule | histone |
Target entity | H3S10 |
Product | H3S10ph |
PMID for information on target | # |
Comment | PBK/TOPK can phosphorylate histone H3 at Ser10 in vitro and in vivo, and mediate its growth-promoting effect through histone H3 modification. Can phosphorylate histone H3 at Ser10 in vitro and in vivo. |
Status of entry | # |