| HGNC approved symbol | PHF2 |
| HGNC ID | HGNC:8920 |
| HGNC approved name | PHD finger protein 2 |
| Entrez gene ID | GeneID:5253 (SSTAR profile) |
| UniProt AC (human) | O75151 |
| UniProt ID (human) | PHF2_HUMAN |
| Pfam domains | PHD PF00628 (8-53) JmjC PF02373 (237-336) JHD PF17811 (340-443) |
| MGI symbol | Phf2 |
| MGI ID | MGI:1338034 |
| UniProt AC (mouse) | Q9WTU0 |
| UniProt ID (mouse) | PHF2_MOUSE |
| HGNC gene family tag | KDM, PHF |
| HGNC gene family description | Chromatin-modifying enzymes / K-demethylases, Zinc fingers, PHD-type |
| Function | Histone modification erase |
| Modification | Histone methylation |
| PMID for information on function | PMID:21532585 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K9me2 |
| Product | H3K9 |
| PMID for information on target | PMID:21532585 |
| Comment | The protein kinase A (PKA)-dependent histone lysine demethylase complex, PHF2-ARID5B. PHF2, a jmjC demethylase, is enzymatically inactive by itself, but becomes an active H3K9Me2 demethylase through PKA-mediated phosphorylation. |
| Status of entry | # |
| Expression range: | 0.0 to 44.87 |
| Mean expression: | 10.17 ± 5.82 |
| Median expression: | 8.7 |