HGNC approved symbol | PRDM4 |
HGNC ID | HGNC:9348 |
HGNC approved name | PR domain containing 4 |
Entrez gene ID | GeneID:11108 (SSTAR profile) |
UniProt AC (human) | Q9UKN5 |
UniProt ID (human) | PRDM4_HUMAN |
Pfam domains | zf_PR_Knuckle PF18445 (366-404) PRDM2_PR PF21549 (414-537) zf-C2H2 PF00096 (618-640, 646-668, 674-696) |
MGI symbol | Prdm4 |
MGI ID | MGI:1920093 |
UniProt AC (mouse) | Q80V63 |
UniProt ID (mouse) | PRDM4_MOUSE |
HGNC gene family tag | ZNF |
HGNC gene family description | Zinc fingers, C2H2-type |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:23048031 |
Protein complex | # |
Target molecule | histone |
Target entity | H4R3 |
Product | H4R3me2s |
PMID for information on target | PMID:23048031 |
Comment | Transcription factor positive regulatory domain 4 (PRDM4) recruits protein arginine methyltransferase 5 (PRMT5) to mediate histone arginine methylation and control neural stem cell proliferation and differentiation. |
Status of entry | # |
Expression range: | 0.0 to 71.1 |
Mean expression: | 9.75 ± 5.22 |
Median expression: | 9.04 |