HGNC approved symbol | PRKAA2 |
HGNC ID | HGNC:9377 |
HGNC approved name | protein kinase, AMP-activated, alpha 2 catalytic subunit |
Entrez gene ID | GeneID:5563 (SSTAR profile) |
UniProt AC (human) | P54646 |
UniProt ID (human) | AAPK2_HUMAN |
Pfam domains | Pkinase PF00069 (16-268) AMPK_alpha_AID PF21147 (288-333) AdenylateSensor PF16579 (401-477) |
MGI symbol | Prkaa2 |
MGI ID | MGI:1336173 |
UniProt AC (mouse) | Q8BRK8 |
UniProt ID (mouse) | AAPK2_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:20647423 |
Protein complex | # |
Target molecule | histone |
Target entity | H2BS36 |
Product | H2BS36ph |
PMID for information on target | # |
Comment | In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph) as a part of AMPK. |
Status of entry | # |
Expression range: | 0.0 to 144.45 |
Mean expression: | 6.39 ± 13.97 |
Median expression: | 1.66 |