| HGNC approved symbol | PRMT2 |
| HGNC ID | HGNC:5186 |
| HGNC approved name | protein arginine methyltransferase 2 |
| Entrez gene ID | GeneID:3275 (SSTAR profile) |
| UniProt AC (human) | P55345 |
| UniProt ID (human) | ANM2_HUMAN |
| Pfam domains | SH3_1 PF00018 (36-82) MTS PF05175 (131-210) domain PF22528 (244-415) |
| MGI symbol | Prmt2 |
| MGI ID | MGI:1316652 |
| UniProt AC (mouse) | Q9R144 |
| UniProt ID (mouse) | ANM2_MOUSE |
| HGNC gene family tag | PRMT |
| HGNC gene family description | Protein arginine methyltransferases |
| Function | Histone modification write |
| Modification | Histone methylation |
| PMID for information on function | PMID:19405910 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H4 |
| Product | H4me |
| PMID for information on target | PMID:19405910 |
| Comment | PRMT2 activity is substantially lower than PRMT1 in vitro, but both enzymes selectively methylate histone H4 and PRMT2, like PRMT1, may act as a transcription co-activator through this modification. |
| Status of entry | # |
| Expression range: | 5.01 to 352.77 |
| Mean expression: | 55.39 ± 32.36 |
| Median expression: | 49.34 |