| HGNC approved symbol | PRMT5 |
| HGNC ID | HGNC:10894 |
| HGNC approved name | protein arginine methyltransferase 5 |
| Entrez gene ID | GeneID:10419 (SSTAR profile) |
| UniProt AC (human) | O14744 |
| UniProt ID (human) | ANM5_HUMAN |
| Pfam domains | PRMT5_TIM PF17285 (36-290) PRMT5 PF05185 (299-464) PRMT5_C PF17286 (467-635) |
| MGI symbol | Prmt5 |
| MGI ID | MGI:1351645 |
| UniProt AC (mouse) | Q8CIG8 |
| UniProt ID (mouse) | ANM5_MOUSE |
| HGNC gene family tag | PRMT |
| HGNC gene family description | Protein arginine methyltransferases |
| Function | Histone modification write |
| Modification | Histone methylation |
| PMID for information on function | PMID:18404153 |
| Protein complex | methylosome |
| Target molecule | histone |
| Target entity | H3R8, H4R3 |
| Product | H3R8me, H4R3me |
| PMID for information on target | PMID:18404153 |
| Comment | PRMT5 regulates gene transcription by methylating histones H3 (R8) and H4. |
| Status of entry | # |
| Expression range: | 0.0 to 136.51 |
| Mean expression: | 25.71 ± 16.95 |
| Median expression: | 23.05 |