| HGNC approved symbol | PRMT6 |
| HGNC ID | HGNC:18241 |
| HGNC approved name | protein arginine methyltransferase 6 |
| Entrez gene ID | GeneID:55170 (SSTAR profile) |
| UniProt AC (human) | Q96LA8 |
| UniProt ID (human) | ANM6_HUMAN |
| Pfam domains | Methyltransf_25 PF13649 (85-182) domain PF22528 (188-362) |
| MGI symbol | Prmt6 |
| MGI ID | MGI:2139971 |
| UniProt AC (mouse) | Q6NZB1 |
| UniProt ID (mouse) | ANM6_MOUSE |
| HGNC gene family tag | PRMT |
| HGNC gene family description | Protein arginine methyltransferases |
| Function | Histone modification write |
| Modification | Histone methylation |
| PMID for information on function | PMID:18079182 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H2AR3, H3R2, H4R4 |
| Product | H2AR3me, H4R3me, H3R2me2a |
| PMID for information on target | PMID:18079182 |
| Comment | PRMT6 methylates histone H3 at R2 and histones H4/H2A at R3 in vitro. Overexpression and knockdown analysis identify PRMT6 as the major H3 R2 methyltransferase in vivo. |
| Status of entry | # |
| Expression range: | 0.0 to 95.06 |
| Mean expression: | 9.37 ± 6.5 |
| Median expression: | 8.85 |