HGNC approved symbol | PRMT8 |
HGNC ID | HGNC:5188 |
HGNC approved name | protein arginine methyltransferase 8 |
Entrez gene ID | GeneID:56341 (SSTAR profile) |
UniProt AC (human) | Q9NR22 |
UniProt ID (human) | ANM8_HUMAN |
Pfam domains | PrmA PF06325 (111-184) domain PF22528 (217-380) |
MGI symbol | Prmt8 |
MGI ID | MGI:3043083 |
UniProt AC (mouse) | Q6PAK3 |
UniProt ID (mouse) | ANM8_MOUSE |
HGNC gene family tag | PRMT |
HGNC gene family description | Protein arginine methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:16051612 |
Protein complex | # |
Target molecule | histone |
Target entity | H4R |
Product | H4Rme |
PMID for information on target | PMID:16051612 |
Comment | PRMT8 preferentially methylates histone H4 and the recombinant forms of GAR and Npl3, thus displaying PRMT1-like substrate specificity. |
Status of entry | # |
Expression range: | 0.0 to 20.38 |
Mean expression: | 0.66 ± 2.62 |
Median expression: | 0.0 |