HGNC approved symbol | PSIP1 |
HGNC ID | HGNC:9527 |
HGNC approved name | PC4 and SFRS1 interacting protein 1 |
Entrez gene ID | GeneID:11168 (SSTAR profile) |
UniProt AC (human) | O75475 |
UniProt ID (human) | PSIP1_HUMAN |
Pfam domains | PWWP PF00855 (8-88) LEDGF PF11467 (350-446) |
MGI symbol | Psip1 |
MGI ID | MGI:2142116 |
UniProt AC (mouse) | Q99JF8 |
UniProt ID (mouse) | PSIP1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:217205545 |
Protein complex | # |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:217205545 |
Comment | The PWWP domain in PSIP1 displays affinity for DNA and chromatin and its chromatin binding ability is crucial for the HIV-1 integration. PSIP1 has been found to promote association of the MLL complex with transcriptionally active chromatin through its PWWP domain. |
Status of entry | # |
Expression range: | 1.6 to 469.88 |
Mean expression: | 64.04 ± 55.33 |
Median expression: | 48.44 |