HGNC approved symbol | PTBP1 |
HGNC ID | HGNC:9583 |
HGNC approved name | Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) |
Entrez gene ID | GeneID:5725 (SSTAR profile) |
UniProt AC (human) | P26599 |
UniProt ID (human) | PTBP1_HUMAN |
Pfam domains | RRM_5 PF13893 (59-144, 340-460) RRM_8 PF11835 (178-258) RRM_1 PF00076 (484-544) |
MGI symbol | Ptbp1 |
MGI ID | MGI:97791 |
UniProt AC (mouse) | P17225 |
UniProt ID (mouse) | PTBP1_MOUSE |
HGNC gene family tag | RBM |
HGNC gene family description | RNA binding motif containing |
Function | RNA modification |
Modification | Alternative splicing |
PMID for information on function | PMID:21518792, PMID:16260624 |
Protein complex | # |
Target molecule | RNA |
Target entity | mRNA |
Product | # |
PMID for information on target | PMID:21518792, PMID:16260624 |
Comment | Regulates exon selection in alpha-tropomyosin mRNA |
Status of entry | New |
Expression range: | 11.65 to 842.94 |
Mean expression: | 173.22 ± 95.77 |
Median expression: | 152.94 |