| HGNC approved symbol | RB1 |
| HGNC ID | HGNC:9884 |
| HGNC approved name | retinoblastoma 1 |
| Entrez gene ID | GeneID:5925 (SSTAR profile) |
| UniProt AC (human) | P06400 |
| UniProt ID (human) | RB_HUMAN |
| Pfam domains | DUF3452 PF11934 (110-229) RB_A PF01858 (375-573) RB_B PF01857 (647-765) Rb_C PF08934 (768-925) |
| MGI symbol | Rb1 |
| MGI ID | MGI:97874 |
| UniProt AC (mouse) | P13405 |
| UniProt ID (mouse) | RB_MOUSE |
| HGNC gene family tag | ENDOLIG |
| HGNC gene family description | Endogenous ligands |
| Function | Chromatin remodeling, Histone modification write |
| Modification | Histone ubiquitination |
| PMID for information on function | PMID:19149898 |
| Protein complex | CREST-BRG1, L3MBTL1 |
| Target molecule | histone |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:19149898 |
| Comment | Hypophosphorylated pRb can repress gene transcription at least partly by remodeling chromatin structure through its interactions with proteins such as HDAC1, BRM and BRG1. |
| Status of entry | # |
| Expression range: | 2.82 to 152.06 |
| Mean expression: | 28.44 ± 19.98 |
| Median expression: | 23.84 |