| HGNC approved symbol | RING1 |
| HGNC ID | HGNC:10018 |
| HGNC approved name | ring finger protein 1 |
| Entrez gene ID | GeneID:6015 (SSTAR profile) |
| UniProt AC (human) | Q06587 |
| UniProt ID (human) | RING1_HUMAN |
| Pfam domains | zf-C3HC4_2 PF13923 (47-87) RAWUL PF16207 (282-400) |
| MGI symbol | Ring1 |
| MGI ID | MGI:1101770 |
| UniProt AC (mouse) | O35730 |
| UniProt ID (mouse) | RING1_MOUSE |
| HGNC gene family tag | RNF |
| HGNC gene family description | RING-type (C3HC4) zinc fingers |
| Function | Histone modification write, Polycomb group (PcG) protein |
| Modification | Histone ubiquitination |
| PMID for information on function | PMID:15386022 |
| Protein complex | PRC1, BCOR, RING2-L3MBTL2, RING2-FBRS |
| Target molecule | histone |
| Target entity | H2AK119 |
| Product | H2AK119ub |
| PMID for information on target | PMID:15386022 |
| Comment | The complex hPRC1L (human Polycomb repressive complex 1-like) is composed of several Polycomb-group proteins including Ring1, Ring2, Bmi1 and HPH2. hPRC1L monoubiquitinates nucleosomal histone H2A at lysine 119. |
| Status of entry | # |
| Expression range: | 2.51 to 154.57 |
| Mean expression: | 38.89 ± 14.39 |
| Median expression: | 36.74 |