HGNC approved symbol | RNF40 |
HGNC ID | HGNC:16867 |
HGNC approved name | ring finger protein 40, E3 ubiquitin protein ligase |
Entrez gene ID | GeneID:9810 (SSTAR profile) |
UniProt AC (human) | O75150 |
UniProt ID (human) | BRE1B_HUMAN |
Pfam domains | zf-C3HC4 PF00097 (948-986) |
MGI symbol | Rnf40 |
MGI ID | MGI:2142048 |
UniProt AC (mouse) | Q3U319 |
UniProt ID (mouse) | BRE1B_MOUSE |
HGNC gene family tag | RNF |
HGNC gene family description | RING-type (C3HC4) zinc fingers |
Function | Histone modification write cofactor |
Modification | Histone ubiquitination |
PMID for information on function | PMID:16307923 |
Protein complex | # |
Target molecule | histone |
Target entity | H2BK121 |
Product | H2BK120ub2 |
PMID for information on target | PMID:16307923 |
Comment | Two copies each of the E3 ligases RNF20 and RNF40 are present in the same complex catalyzing histone H2B-K120 monoubiquitination. The complex that catalyzes histone H2A-K119 monoubiquitination also contains two E3 ligases, Ring1 and Ring2. |
Status of entry | # |