| HGNC approved symbol | RPS6KA3 |
| HGNC ID | HGNC:10432 |
| HGNC approved name | ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| Entrez gene ID | GeneID:6197 (SSTAR profile) |
| UniProt AC (human) | P51812 |
| UniProt ID (human) | KS6A3_HUMAN |
| Pfam domains | Pkinase PF00069 (68-327, 422-679) Pkinase_C PF00433 (351-387) |
| MGI symbol | Rps6ka3 |
| MGI ID | MGI:104557 |
| UniProt AC (mouse) | P18654 |
| UniProt ID (mouse) | KS6A3_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification write cofactor |
| Modification | Histone phosphorylation |
| PMID for information on function | PMID:10436156 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3S10 |
| Product | H3S10ph |
| PMID for information on target | PMID:10436156 |
| Comment | Is required for EGF-stimulated phosphorylation of CREB1 and histone H3 at 'Ser-10', which results in the subsequent transcriptional activation of several immediate-early genes. |
| Status of entry | # |
| Expression range: | 2.14 to 392.65 |
| Mean expression: | 32.99 ± 33.37 |
| Median expression: | 24.19 |