| HGNC approved symbol | RPS6KA4 |
| HGNC ID | HGNC:10433 |
| HGNC approved name | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| Entrez gene ID | GeneID:8986 (SSTAR profile) |
| UniProt AC (human) | O75676 |
| UniProt ID (human) | KS6A4_HUMAN |
| Pfam domains | Pkinase PF00069 (33-301, 413-673) Pkinase_C PF00433 (322-361) |
| MGI symbol | Rps6ka4 |
| MGI ID | MGI:1930076 |
| UniProt AC (mouse) | Q9Z2B9 |
| UniProt ID (mouse) | KS6A4_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification write |
| Modification | Histone phosphorylation |
| PMID for information on function | PMID:12773393 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3S10, H3S28 |
| Product | H3S10ph, H3S28ph |
| PMID for information on target | PMID:12773393 |
| Comment | The MSKs, particularly MSK2=RPS6KA4, but not RSK2, are the major histone H3 and HMG-14 kinases. |
| Status of entry | # |
| Expression range: | 0.0 to 141.47 |
| Mean expression: | 20.72 ± 15.61 |
| Median expression: | 17.57 |