| HGNC approved symbol | RRP8 |
| HGNC ID | HGNC:29030 |
| HGNC approved name | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
| Entrez gene ID | GeneID:23378
(SSTAR profile) |
| UniProt AC (human) | O43159 |
| UniProt ID (human) | RRP8_HUMAN |
| Pfam domains | Methyltransf_8 PF05148 (239-456) |
| MGI symbol | Rrp8 |
| MGI ID | MGI:1914251 |
| UniProt AC (mouse) | Q9DB85 |
| UniProt ID (mouse) | RRP8_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification cofactor |
| Modification | # |
| PMID for information on function | PMID:18485871 |
| Protein complex | eNoSc |
| Target molecule | histone |
| Target entity | H3ac |
| Product | H3K9me2 |
| PMID for information on target | # |
| Comment | A component of the eNoSC complex, that mediates silencing of rDNA by recruiting histone-modifying enzymes, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. |
| Status of entry | # |