HGNC approved symbol | RUVBL2 |
HGNC ID | HGNC:10475 |
HGNC approved name | RuvB-like AAA ATPase 2 |
Entrez gene ID | GeneID:10856 (SSTAR profile) |
UniProt AC (human) | Q9Y230 |
UniProt ID (human) | RUVB2_HUMAN |
Pfam domains | TIP49 PF06068 (21-364) TIP49_C PF17856 (370-435) |
MGI symbol | Ruvbl2 |
MGI ID | MGI:1342299 |
UniProt AC (mouse) | Q9WTM5 |
UniProt ID (mouse) | RUVB2_MOUSE |
HGNC gene family tag | INO80, AATP |
HGNC gene family description | INO80 complex subunits, ATPases / AAA-type |
Function | Chromatin remodeling cofactor |
Modification | # |
PMID for information on function | PMID:18026119 |
Protein complex | Ino80, SWR, NuA4, NuA4-related complex, CHD8, MLL2/3, MLL4/WBP7, SRCAP |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:18026119 |
Comment | The seven human INO80 complex components include TIP49A and TIP49B (previously identified as ‘RuvB-like’ proteins, and labeled RUVBL1 and RUVBL2). |
Status of entry | # |
Expression range: | 0.0 to 295.87 |
Mean expression: | 38.74 ± 29.89 |
Median expression: | 30.95 |