HGNC approved symbol | SAP130 |
HGNC ID | HGNC:29813 |
HGNC approved name | Sin3A-associated protein, 130kDa |
Entrez gene ID | GeneID:79595 (SSTAR profile) |
UniProt AC (human) | Q9H0E3 |
UniProt ID (human) | SP130_HUMAN |
Pfam domains | SAP130_C PF16014 (654-1033) |
MGI symbol | Sap130 |
MGI ID | MGI:1919782 |
UniProt AC (mouse) | Q8BIH0 |
UniProt ID (mouse) | SP130_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase cofactor |
Modification | Histone acetylation |
PMID for information on function | PMID:12724404 |
Protein complex | # |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:12724404 |
Comment | SAP130 has a repression domain at its C terminus that interacts with the mSin3A-HDAC complex and an N-terminal domain that probably mediates an interaction with a transcriptional activator. |
Status of entry | # |