HGNC approved symbol | SCMH1 |
HGNC ID | HGNC:19003 |
HGNC approved name | sex comb on midleg homolog 1 (Drosophila) |
Entrez gene ID | GeneID:22955 (SSTAR profile) |
UniProt AC (human) | Q96GD3 |
UniProt ID (human) | SCMH1_HUMAN |
Pfam domains | MBT PF02820 (62-129, 171-236) RBR PF17208 (269-333) SLED PF12140 (357-471) SAM_1 PF00536 (592-656) |
MGI symbol | Scmh1 |
MGI ID | MGI:1352762 |
UniProt AC (mouse) | Q8K214 |
UniProt ID (mouse) | SCMH1_MOUSE |
HGNC gene family tag | SAMD |
HGNC gene family description | Sterile alpha motif (SAM) domain containing |
Function | Polycomb group (PcG) protein |
Modification | # |
PMID for information on function | PMID:23356856 |
Protein complex | PRC1 |
Target molecule | # |
Target entity | # |
Product | # |
PMID for information on target | PMID:23356856 |
Comment | SCMH1 is part of a polycomb group complex 1 (PcG1) involved in transcriptional silencing and proteosomal degradation for the Geminin protein, important for regulation of replication and maintenance of undifferentiated states. |
Status of entry | # |
Expression range: | 0.0 to 125.16 |
Mean expression: | 12.35 ± 9.55 |
Median expression: | 10.58 |