| HGNC approved symbol | SETD1A |
| HGNC ID | HGNC:29010 |
| HGNC approved name | SET domain containing 1A |
| Entrez gene ID | GeneID:9739 (SSTAR profile) |
| UniProt AC (human) | O15047 |
| UniProt ID (human) | SET1A_HUMAN |
| Pfam domains | RRM_1 PF00076 (97-166) N-SET PF11764 (1419-1559) SET PF00856 (1580-1685) |
| MGI symbol | Setd1a |
| MGI ID | MGI:2446244 |
| UniProt AC (mouse) | # |
| UniProt ID (mouse) | # |
| HGNC gene family tag | KMT, RBM |
| HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases, RNA binding motif (RRM) containing |
| Function | Histone modification write |
| Modification | Histone methylation |
| PMID for information on function | PMID:17355966 |
| Protein complex | COMPASS |
| Target molecule | histone |
| Target entity | H3K4 |
| Product | H3K4me |
| PMID for information on target | PMID:17355966 |
| Comment | The CFP1 complex contains human homologues of the COMPASS complex, including Set1A=SETD1A, Wdr5, Ash2, Rbbp5, and Wdr82 (previously denoted hSwd2). The human Set1A-CFP1 complex exhibits histone H3-Lys4 methyltransferase activity in vitro. |
| Status of entry | # |
| Expression range: | 0.94 to 40.88 |
| Mean expression: | 9.34 ± 4.79 |
| Median expression: | 8.46 |