HGNC approved symbol | SETD1B |
HGNC ID | HGNC:29187 |
HGNC approved name | SET domain containing 1B |
Entrez gene ID | GeneID:23067 (SSTAR profile) |
UniProt AC (human) | Q9UPS6 |
UniProt ID (human) | SET1B_HUMAN |
Pfam domains | RRM_1 PF00076 (104-175) N-SET PF11764 (1676-1821) SET PF00856 (1839-1944) |
MGI symbol | Setd1b |
MGI ID | MGI:2652820 |
UniProt AC (mouse) | Q8CFT2 |
UniProt ID (mouse) | SET1B_MOUSE |
HGNC gene family tag | KMT, RBM |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases, RNA binding motif (RRM) containing |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:17355966 |
Protein complex | COMPASS |
Target molecule | histone |
Target entity | H3K4 |
Product | H3K4me |
PMID for information on target | PMID:17355966 |
Comment | The extensive homology between Set1A and Set1B=SETD1B, particularly throughout the SET domain, suggests that Set1B functions as a histone methyltransferase. |
Status of entry | # |
Expression range: | 1.72 to 117.69 |
Mean expression: | 19.42 ± 14.06 |
Median expression: | 15.95 |