HGNC approved symbol | SETD3 |
HGNC ID | HGNC:20493 |
HGNC approved name | SET domain containing 3 |
Entrez gene ID | GeneID:84193 (SSTAR profile) |
UniProt AC (human) | Q86TU7 |
UniProt ID (human) | SETD3_HUMAN |
Pfam domains | SET PF00856 (105-314) Rubis-subs-bind PF09273 (345-475) |
MGI symbol | Setd3 |
MGI ID | MGI:1289184 |
UniProt AC (mouse) | Q91WC0 |
UniProt ID (mouse) | SETD3_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | # |
Protein complex | # |
Target molecule | histone |
Target entity | H3K36 |
Product | H3K36me |
PMID for information on target | # |
Comment | Histone methyltransferase that methylates 'Lys-36' of histone H3 (H3K36me). H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. (Annotated by similarity.) |
Status of entry | # |
Expression range: | 2.53 to 98.88 |
Mean expression: | 23.73 ± 12.35 |
Median expression: | 21.15 |