HGNC approved symbol | SETDB2 |
HGNC ID | HGNC:20263 |
HGNC approved name | SET domain, bifurcated 2 |
Entrez gene ID | GeneID:83852 (SSTAR profile) |
UniProt AC (human) | Q96T68 |
UniProt ID (human) | SETB2_HUMAN |
Pfam domains | MBD PF01429 (163-229) Pre-SET PF05033 (247-359) SET PF00856 (623-694) |
MGI symbol | Setdb2 |
MGI ID | MGI:2685139 |
UniProt AC (mouse) | Q8C267 |
UniProt ID (mouse) | SETB2_MOUSE |
HGNC gene family tag | KMT |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:20404330 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9 |
Product | H3K9me3 |
PMID for information on target | PMID:20404330 |
Comment | A member of the histone H3K9 methyltransferase family named CLLD8 (or SETDB2 or KMT1F). |
Status of entry | # |
Expression range: | 0.0 to 136.78 |
Mean expression: | 12.95 ± 15.08 |
Median expression: | 7.97 |